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[15] Serious but infrequent events-such as angioedema, bronchospasm, hypotension, or urticaria-reflect IgE-mediated hypersensitivity and may require desensitization or substitution with hydroxocobalamin
The safety and pharmacology data behind this profile isnt thin six controlled trials covering roughly 900 participants, compiled in Stier et al
Using it off-label for weight loss would require much higher doses than it is currently approved for and it would not be cost effective
Vitamin B12 shots are only available by prescription following a clinical diagnosis of low levels
