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Once weekly, subcutaneous semaglutide should be injected subcutaneously (under the skin) into the upper arm, abdomen, or thigh
From 5 October 2018 to 1 February 2019, 304 participants were randomly assigned to semaglutide 2.4 mg (n = 152) or placebo (n = 152), 92.8% of whom completed the trial (attended the end-of-trial safety visit)
Furthermore, it presents, at position 20, a C20 fatty acid chain attached via a linker to the lysine residue, which enables the molecule to bind circulating albumin with high affinity, thus increasing the half-life up to 5 days (39), allowing a single weekly subcutaneous administration
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For patients preferring in office injections our nurses can administer the injections for ongoing care
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