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A small subset of people may not lose significant weight at all on GLP-1s, which is a different issue from plateauing after initial loss
October 8, 2022
Yue SJ, Wang WX, Zhang L, Liu J, Feng WW, Gao H, et al
This MMP-1 inhibition occurs through interference with AP-1 transcription factor binding to the MMP-1 promoter region, reducing collagen degradation rates in dermal matrices
Late dumping syndrome is thought to be from a rapid spike in blood glucose levels from this causing an excessive amount of insulin being secreted from the pancreas and an excessive GLP-1 response resulting in a hypoglycaemic episode 13 h after the meal [9]
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