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189 In parallel, error-prone DNA damage tolerance mechanisms, such as translesion synthesis (TLS), contribute to therapy evasion

Overall, this can ultimately lead to the lysis of the vacuole, releasing meningococci into the cytosol

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Laboratory studies show GHK-Cu treatment results in enhanced capillary-like tube formation in three-dimensional culture systems, with treated endothelial cells forming more extensive networks with improved branch points and connectivity compared to untreated controls, indicating promotion of both early vessel sprouting and later network organization phases