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Christofk, H
The REDEFINE 1 and 2 trials evaluated the effects of cagrilintide 2.4 mg and semaglutide 2.4 mg on weight loss in patients with overweight or obesity, with and without type 2 diabetes
The key differences come down to absorption rate, plasma concentration, and time to results
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Cagrilintide is engineered around that problem: it is a modified, lipidated peptide that acts as a dual amylin and calcitonin receptor agonist and is stable enough for once-weekly subcutaneous dosing
This felt like genuine healing from the inside out
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