This pocket is formed by residues in transmembrane helices 1 (TM1), 2 (TM2), 3 (TM3), and 7 (TM7), along with contributions from extracellular loop 2 (ECL2)
Patients using this combination often report feeling stronger and more capable during their weight loss journey, rather than the weakness and fatigue that can accompany rapid weight loss
Symptoms often appear suddenly, sometimes within hours of ingestion, and can be more severe than those of viral gastroenteritis
In 2006, Competitive Technologies, a technology transfer company operating on behalf of the University of Arizona, licensed the drug as a tanning agent
Given that T2D itself is a known risk factor for pancreatic cancer, the findings open new doors for understanding the cancer prevention potential of diabetes drugs