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While the impact of cigarette smoking on the redox balance of several tissues has been extensively studied, its specific role in triggering oxidative injury in erythrocytes has only recently gained attention
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The classical pathway is initiated by pathogenic stimuli, which activate pattern recognition receptors (PRRs) along with caspase recruitment domain- or pyrin domain-containing proteins (159, 163)
This may happen because glutathione interacts with detoxification pathways in the liver, which temporarily trigger mild digestive upset
123 A central paradigm is the evolutionary selection of resistant clones under therapeutic pressure
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