Most injectable GLP-1 medicationsincluding semaglutide (Wegovy) and tirzepatide (Zepbound)are given once a week
There isnt enough data to confirm that microdosing can help you live longer, says clinical pharmacist practitioner Anne Kom of the University of North Carolina Medical Center in Chapel Hill, who published a 2025 e-letter about microdosing GLP-1s in Diabetes Care
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For the new study, researchers recruited 20 people with obesity, half of whom were taking a GLP-1 drug
Conservative escalation (monthly increases) generates slower initial progress but better long-term consistency and ultimately superior total weight loss for many people