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it is a catecholamine derived from the amino acid tyrosine , functioning as both a hormone and neurotransmitter
Expert consensus suggests considering pharmacotherapy when there is: Significant weight regain from nadir weight BMI 27 kg/m with obesity-related comorbidities or BMI 30 kg/m Absence of anatomical complications requiring surgical revision Adequate adherence to nutritional and behavioral recommendations Patient willingness to engage in long-term pharmacotherapy The American Association of Clinical Endocrinologists (AACE) and American College of Endocrinology (ACE) guidelines emphasize that pharmacologic therapy should complement, not replace, lifestyle interventions and ongoing bariatric surgical follow-up
There was a 2015 Phase I human trial registered to study safety and pharmacokinetics, but published results are conspicuously missing
PMID 37074394
Eat Small, Frequent Meals Eating smaller portions more often makes digestion easier and helps prevent nausea
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