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Kaminski MR, Lambert KA, Raspovic A, et al
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How Retatrutide Works in Research Retatrutide functions as a triple receptor agonist with differentiated activity across GLP-1, GIP, and glucagon receptors
These medications alter gut motility and can affect how quickly food moves through your digestive system
The preference for metformin as the initial agent is based on its durable efficacy in lowering A1C, absence of risk for hypoglycemia or weight gain, relatively mild side-effect profile, longterm safety track record, and affordability
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