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Semaglutide is a GLP-1 agonist medication that works by mimicking the effects of the hormone glucagon-like peptide-1 (GLP-1)
The goal is progressive loading that stimulates further tissue adaptation without exceeding the healing tissues capacity
The highly specific sequence spanning from position 30 to position 39 is GPSSGAPPPS
Additional genome-wide association analysis involving 61,488 coronary artery disease patients and 163,728 controls found that the variant at rs10305492 in GLP1R is significantly associated with reduced risk of coronary artery disease, independent of the effect on reduced fasting glucose
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