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4,5,6 The term pernicious anaemia refers to an autoimmune disease that destroys the parietal cells, leading to a lack of IF and thus B12 deficiency

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This likely contributes to GHK-Cus cardiovascular and tissue protective effects

Sample preparation for serum metabolite and untargeted/targeted metabolomic mass spectrometry methods performed in this study were based on previously established protocol (Figure 1