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Activating upstream targets of the GSH system The key upstream target for GSH system modulation is generally considered to be Nrf2, a redox-sensitive regulator
The drug should only be used if the potential benefit justifies the potential risk
2002 Oct;175(1):19-31
Pignata S, De Placido S, Biamonte R, Scambia G, Di Vagno G, Colucci G, Febbraro A, Marinaccio M, Lombardi AV, Manzione L (2006) Residual neurotoxicity in ovarian cancer patients in clinical remission after first-line chemotherapy with carboplatin and paclitaxel: the multicenter italian trial in ovarian cancer (MITO-4) retrospective study
How long you feel the effects can depend on your starting levels, which is why people with a larger deficiency sometimes notice the benefits over a longer stretch
