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This is particularly advantageous for individuals who may not obtain sufficient vitamin B12 through their regular diet

Nature 575 , 688692 (2019)

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Kaku, K., Yamada, Y., Watada, H., Abiko, A., Nishida, T., Zacho, J., & Kiyosue, A

Genetic experiments using mice lacking the IFN-I receptor, along with Chac2-deficient HL60 cells, showed that disrupting IFN-I signaling prevented Chac2 activation, GSH metabolic reprogramming, and N1 polarization