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Weight regain occurred in STEP 4 after semaglutide therapy ended, thus revealing the necessity for sustained patient treatment
Dosing: Three times daily with meals Must take with or within 1 hour of meals containing fat Cost: Prescription (Xenical 120 mg): $100-$200/month OTC (Alli 60 mg): $40-$60/month Who Should Consider: Very few patients benefit May be option if all other medications contraindicated Extremely motivated to follow low-fat diet Dont mind frequent GI side effects Most weight loss specialists dont recommend orlistat due to poor effectiveness and troublesome side effects
Range of ocular complications extends beyond NAION In addition to NAION, the report notes that GLP-1RAs may worsen age-related macular degeneration and accelerate diabetic retinopathy progression
When we stop these medications, especially, the hunger comes back very strongly, so there is a large association between stopping the medication and having that weight regain, says Dr
Even patients who are not in withdrawal are highly sensitive to withdrawal-like symptoms and may misinterpret nausea as the beginning of opioid withdrawal
