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As to the pi class, GSTP1-1 point mutations in both exon 5 (codon 105) and exon 6 (codon 114) were observed and shown to have an impact on the enzymatic activity 32

There are currently more than 1.3 billion liver disease patients worldwide, and viral hepatitis, especially hepatitis B, is still the main cause of chronic liver disease and end-stage liver disease

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Dihexa is markedly hydrophobic as a consequence of its hexanoyl and aminohexanoic modifications, and dissolves poorly in plain aqueous solvent