The primary stimuli for secreting GLP-1 are meals rich in fats and carbohydrates, and GLP-1s main action is to signal satiety to the brain
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Abbreviations GLP-1: Glucagon Like Peptide-1 CV: Cardio Vascular DPP-4: DiPeptidylPeptidase-4 USFDA: United States Food & Drug Administration Aib: 2-Aminoisobutyric acid SNAC: Sodium-N-[8-(2-hydroxybenzoyl)amino]caprylate SUSTAIN: Semaglutide Unabated Sustainability in Treatment of Type 2 Diabetes FPG: Fasting Plasma Glucose HOMA-B: Homeostasis model assessment of -cell function ER: Extended release DXA: Dual energy X-ray Absorptiometry OAD: Oral Antidiabetic Drugs SGLT-2: Sodium GLucose co-Transporter-2 SMBG: Self-Monitoring of Blood Glucose PIONEER: Peptide Innovation for Early Diabetes Treatment EMA: European Medicines Agency References Garber AJ, Abrahamson MJ, Barzilay JI, Blonde L, Bloomgarden ZT, Bush MA, Dagogo-Jack S, DeFronzo RA, Einhorn D, Fonseca VA, Garber JR, Garvey WT, Grunberger G, Handelsman Y, Hirsch IB, Jellinger PS, McGill JB, Mechanick JI, Rosenblit PD, Umpierrez GE
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