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L-carnitine is found in cells and tissues either as free L-carnitine or as acylcarnitines, i.e., L-carnitine bound to an acyl group
TDP-43 mutations causing amyotrophic lateral sclerosis are associated with altered expression of RNA-binding protein hnRNP K and affect the Nrf2 antioxidant pathway
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Low levels may worsen liver stress and cell death
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