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And these results, he said, are paradigm-shifting, as these new medications may soon become the first step in effective hypertension control for people with obesitydelivering blood pressure reductions that rival those of traditional antihypertensive medications, along with many additional benefits. Clinically Meaningful Impact on BP Prior research has shown that weight gain increases blood pressure and that substantial weight losswith bariatric surgery or caloric restriction, for instancereduces it

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The safest standard plan is to stop it when pregnancy is recognized and, for planned pregnancy, stop it at least 2 months before conception

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