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Results L2-Cmu is a selective antagonist to the IGF-1R and hybrids L2-Cmu was developed as a murinized version of the L2-C mAb at Amgen Inc
Its main mechanism involves the stimulation of angiogenesis via the VEGF-eNOS-NO pathway, fibroblast migration, and type I collagen synthesis
Begas, P., Staudacher, V
Study Duration: Daily, up to 16 weeks
sponsored a 24-week, randomized, placebo-controlled obesity trial (N=536) testing oral AOD-9604 at doses of 1 mg, 5 mg, 10 mg, and 20 mg daily
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