Presented for research literature review only Bellinghieri G et al
18, 2025, by Lindsey Shapiro, PhD Fact-checked by Marta Figueiredo, PhD Prader-Willi syndrome (PWS) is a rare condition characterized by a wide range of symptoms, typically including insatiable hunger, slow growth, intellectual disability, and behavioral issues, that are caused by genetic abnormalities affecting chromosome 15
Results are modeled estimates 95% Bayesian credible intervals apply to Plot 1 and Plot 2
Needle length matters too
Dosing protocols Phase 2 clinical trials used a titration schedule starting at 0.5mg weekly, escalating through 1mg, 2mg, 4mg, 8mg, and reaching maintenance doses of up to 12mg weekly over several months