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At the cellular level, Tirzepatide binding to GLP-1 receptors in the hypothalamus directly modulates hunger and satiety signaling

Inflammation Reduction Semaglutides well-documented anti-inflammatory effects may reduce the chronic neuroinflammation that lowers migraine threshold

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If injected into a vein, these effects may intensify

Ozempic and NAION Vision Loss Multiple studies since 2024 suggest an association between semaglutide and an increased risk of NAION (non-arteritic anterior ischemic optic neuropathy)