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Diary cards were provided to participants on days 1, 7, 14, and 21, onto which participants were instructed to record their temperature, adverse events (AEs), medication, and supplementation

Very large meals can also be difficult

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Some individuals prefer divided doses throughout the day to maintain stable plasma concentrations, while others find single daily doses more convenient

For systemic or injectable use, the safest guidance this article can offer is that it falls outside the validated evidence base and should not be undertaken casually