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Opioid System Involvement: May interact with opioid peptides, explaining analgesic effects [Sudakov 1987]

A related study showed that after doxorubicin was injected into mice, expression of GPX4 was downregulated, mitochondrial lipid peroxidation was caused by the DOX-Fe 2+ complex, and mitochondria-dependent ferroptosis was the main cause of DIC

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But the preclinical data, combined with growing clinical observations, suggests these compounds may support disc healing through mechanisms that conventional treatments simply do not address