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Patients who are pregnant, breastfeeding, have complex medical conditions, untreated sleep disorders, cardiovascular concerns, psychiatric instability, autoimmune concerns, or multiple medication interactions should be especially cautious
Hormones (Athens) 7 , 2427 (2008)
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Because cysteine is the least abundant of the three precursors in most physiological settings, cysteine availability is the principal bottleneck for GSH synthesis -- which is precisely the leverage point NAC addresses as a precursor
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