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Extensive clinical trials in diabetic and non-diabetic subjects have proven its long-term weight reduction effects
GIP is the main incretin hormone in healthy people, causative of most the incretin effects, but the insulin response after GIP secretion in type 2 diabetes mellitus (T2DM) is strongly reduced
These observations align with improved peripheral blood flow from nitric oxide-mediated vasodilation, though they could also reflect placebo effects or confirmation bias
Daily options include liraglutide (Victoza, Saxenda), while weekly injectable formulations include semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and exenatide extended-release (Bydureon BCise)
In this case, were likely in a weight-loss plateau
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