While the exact causes of these erythrocyte changes are due to fibrin amyloid microclots or other factors, such as ROS (which can cause RBC changes as well [367, 368]), remain unclear, they likely contribute to the oxidative stress observed in Long COVID [369, 370]
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J Neurosci
Thus, the CXXC motif present in the ER oxidoreductases ensures efficient reduction or isomerization