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Bottom Line BPC157 remains an experimental peptide with mechanistic plausibility derived from preclinical models but insufficient human data to claim clinical efficacy or long term safety, and its regulatory and anti doping status increase risk for patients and athletes considering unsupervised use
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The findings bear implications in developing novel therapeutic interventions for chronic hypoxia-related brain disorders
The FLOW trial also highlights the renal protective effects of GLP-1RAs, suggesting a close link between renal and cardiovascular benefits, which warrants further mechanistic studies (256)
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