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Therapeutic efficacy evaluation of TYR-activated anti-cancer prodrugs in a mouse drug-resistant melanoma model Encouraged by the strong anti-proliferation effects observed in vitro, we further explored the therapeutic potential of TYR-activated anti-cancer prodrugs on a DR-B16F10 melanoma-bearing mouse model

once receptors are saturated, adding more is simply wasteful

Epigenetic modifications also play crucial roles in mediating tumour growth and metastasis by regulating pyroptosis-related pathways [71]

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Reduced GSH was purchased from Sigma (G4251)