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Conversely, reversal of GLP-1(936)s glucagonostatic effect might explain the dramatic elevation of circulating glucagon observed after pharmacological/genetic inhibition of the GCGRs [43, 53, 65, 66], an effect that has been attributed to AA-induced stimulation of alpha cell proliferation

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Among prediabetic participants, 87.7% reverted to normoglycemia with the combination, compared with 32.2% on placebo

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