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GIP, a sister incretin hormone to GLP-1, also plays a role in glucose homeostasis
PMID: 10496658
China Patent CN101921712 (B) Perricone C, Carolis C de, Perricone R (2009) Glutathione: a key player in autoimmunity
For example, GLP-1R in adipocytes can directly regulate apoptosis and preadipocyte proliferation by activating the adenylate cyclase/cyclic adenosine monophosphate (AC/cAMP) signaling pathway and various cell signaling cascades, including extracellular signal-regulated kinase (ERK), protein kinase C (PKC), and protein kinase B (AKT) [41,46]
Furthermore, L-carnitine works synergistically with endothelial pathways to improve nitric oxide production, supporting healthy blood vessel constriction and dilation
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