Because tesamorelin works via the GH axis rather than the incretin system, its metabolic effects are more targeted and narrower in scope
However, its a good idea to have clean feet to reduce the risk of infection from a needle puncture through the skin
The triceps area (back of the upper arm, midway between shoulder and elbow) is harder to reach for self-injection and has the most variable fat layer
doi:10.1034/j.1399-5618.2002.01180.x 16
Regarding the participants with MCI or AD, defined based on a clinical dementia rating (CDR) global score of 0.5 or 1, although the 18-month treatment with exenatide was safe and well-tolerated, it did not significantly affect clinical and cognitive measures, nor did it affect MRI cortical thickness and volume or most biomarkers in the cerebrospinal fluid (CSF), plasma, and plasma neuronal extracellular vesicles (EVs)