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The amount of food intake was monitored at HFD period (16 weeks) to assess consumption and changes in body weight from baseline to post-intervention (HFD) was calculated

These activated Smads form a complex with Smad4, which translocates to the nucleus and promotes the expression of pro-fibrotic genes [24], such as Type I Collagen alpha 1 (COL1A1) and Fibronectin and Connective Tissue Growth Factor (CTGF)

Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice

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Free Radic Res 2008