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doi: 10.1523/JNEUROSCI.0728-09.2009, 64 MoreauD.WangC

To date, 731 participants have been enrolled to compare the long-term effects of tirzepatide versus placebo in improving major adverse cardiovascular events (MACE), weight, and metabolic indicators, and to assess its efficacy in enhancing exercise tolerance in heart failure patients

This critical gap in our understanding explains why neurovascular injury and the resulting disability may persist and even worsen, despite the re-establishment of blood flow to the affected cerebral regions [1, 5, 6]

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