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The consequent impairment in oxalate homeostasis can trigger localized and systemic inflammation, progressive kidney disease and cardiovascular complications, including sudden cardiac death
Frontiers in Pharmacology, 11 , Article 1132
While ROS play essential signaling roles and help regulate cellular redox status, their over-accumulation disrupts cellular integrity, leading to lipid peroxidation, protein degradation, nucleic acid damage, and ultimately cell death
Partial responders may benefit from dose adjustments within the 1-3 mg daily range or increased topical application frequency
And staying engaged and learning new things as you age can keep memory sharp, too
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