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Setin-Suero E, Surez-Pinilla M, Surez-Pinilla P, Crespo-Facorro B, Ayesa-Arriola R
[8] [11] [12] [13] [14] [15] [16] [17] A 1961 report by Paul OHollaren, MD, of Shadel Hospital in Seattle, Washington, led to a study that led to the widespread use of IV infusions of NAD+ for the treatment of addiction
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The N-acetyl capping at the N-terminus and C-terminal amidation protect the peptide from exopeptidase degradation aminopeptidases at the N-terminus and carboxypeptidases at the C-terminus extending its biological half-life compared to unmodified Epitalon
Injection sites can be near the area of injury or systemically, depending on the goal of treatment
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