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The rapid weight loss associated with semaglutide can lead to a decrease in muscle mass and fat that support the veins, potentially worsening these conditions
FDA-approved GLP-1 receptor agonists include semaglutide (Wegovy, Ozempic), tirzepatide (Mounjaro, Zepbound), liraglutide (Saxenda, Victoza), dulaglutide (Trulicity), and exenatide (Byetta, Bydureon)
Similarly to insulin, amylin has similar secretion patterns with low fasting levels and marked increases following meals [29, 30]
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