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44 In the latest clinical trials, namely the STEP-HFpEF and STEP-HFpEF-DM trials, semaglutide resulted in a significant reduction in C-reactive protein levels versus placebo in a pooled analysis of the two trials (43% versus 10%, respectively)

Colucci S, Mori G, Vaira S, Brunetti G, Greco G, Mancini L, Simone GM, Sardelli F, Koverech A, Zallone A, Grano M: L-carnitine and isovaleryl L-carnitine fumarate positively affect human osteoblast proliferation and differentiation in vitro

While compounded meds are affordable, brand-name options still run hundreds to thousands per month, and Hers doesnt provide reimbursement pathways

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Researchers are now taking a closer look at these other potential indications for GLP-1 agonists