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10.1038/nrgastro.2009.35 381 RodaA.Serra-MirG.Montoliu-GayaL.TiesslerL.VillegasS
doi:10.1016/j.ajcnut.2024.05.019 Sohouli MH, Almuqayyid F, Alfardous Alazm A, et al
The most important serious side effects include acute pancreatitis (severe persistent abdominal pain radiating to the back, though clinical trials found similar pancreatitis rates to comparators), severe dehydration from persistent vomiting or diarrhea (signs include dizziness, decreased urination, extreme thirst), gallbladder disease including cholecystitis or cholelithiasis (right upper quadrant pain, fever, jaundice), severe allergic reactions (difficulty breathing, swelling of face or throat), and severe hypoglycemia when combined with insulin or sulfonylureas (confusion, loss of consciousness, seizures)
However, researchers and clinicians have observed its potential in a much broader population, especially in the context of: Visceral adiposity (deep belly fat) Growth hormone deficiency Cognitive aging Cardiometabolic risk reduction Its appeal lies in the ability to elevate IGF-1 (insulin-like growth factor-1) levels while preserving the bodys natural feedback mechanisms
Benefits of Semaglutide For Patients With Obesity And Alcohol Use Disorder Patients with both obesity and alcohol use disorder face unique challenges that require comprehensive care
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