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Similarly, exercise mimetics that modulate microglial activation, such as the PPAR agonist thiazolidinediones (TZDs), can recapitulate these anti-inflammatory effects, thereby safeguarding neuronal integrity and establishing a more permissive regenerative microenvironment [235]

In contrast, B complex supplements provide all eight B vitamins in varying amounts, usually formulated to deliver approximately 100% or more of the recommended daily intake for each vitamin