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For example, if MetR is impaired, the management of iron homeostasis is at risk

Competitive Inhibition and VMAT Reverse Transport : Amphetamines are also recognized as substrates by VMAT2 and actively compete with endogenous dopamine for vesicular uptake, further inhibiting normal dopamine storage (Wimalasena 2011)

The mechanism may involve PPARG-mediated upregulation of fatty acid binding protein, lipoprotein lipase, and lipocalin in adipocytes, thereby enhancing lipogenesis (Kim et al., 2018)