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Science 339 , 222226 (2013)

The 2006 study showed BPC-157's effects could not be fully blocked by L-NAME (a standard NO inhibitor), suggesting the peptide works through parallel pathways that remain active even when the primary NO system is pharmacologically suppressed

It was suggested that it could be injected just under the skin near the belly button and may have helped with injuries around the body, systemically targeting inflammation

The two peptides address different but complementary stages of the healing cascade: BPC-157 handles localized repair signaling, TB-500 handles systemic mobilization and anti-inflammatory signaling

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