Clinical trials showed modest fat loss of roughly 2-3 kg over 12 weeks, and the compound was never approved as a pharmaceutical because efficacy did not meet the threshold for drug registration (Heffernan et al., 2001)
J Exp Clin Cancer Res 34:71 Rosenson RS, Gandra SR, McKendrick J, Dent R, Wieffer H, Cheng LI, Catapano AL, Oh P, Kees Hovingh G, Stroes ES (2017) Identification and management of statin-associated symptoms in clinical practice: extension of a clinician survey to 12 further countries
Methylcobalamin is also known for its potential benefits in neurological health, making it a good choice if youre looking for more targeted support
HCT116 cells were treated with C1-27 (100 nM) for 2 h, followed by drug washout
10.1016/bs.afnr.2019.02.008 44 RinninellaE.RaoulP.CintoniM.FranceschiF.MiggianoG