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Molecular biology and genomics techniques should be used to conduct in-depth studies on the potential toxicity to aquatic organisms and the mechanisms of action of SSRIs to thoroughly study the mechanisms by which SSRIs affect germ cells, embryonic development, and reproductive system maturation

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It is a substrate for -ketoglutarate dehydrogenase (OGDH) in oxidative reactions generating succinyl-CoA and isocitrate dehydrogenase 1 (IDH1) or isocitrate dehydrogenase 2 (IDH2), which catalyze the reductive carboxylation reaction converting -KG to isocitrate

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