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2012 Feb;35(2):446-54

Experts also recommend that excessive alcohol and toxins be avoided

The maximum dose allowed by health authorities is 3000 mg

A recent study investigated the effects of GLP-1R agonists in a multi-hit mouse model in which the combination of a high-fat diet and angiotensin II-induced a cardiometabolic HFpEF phenotype that resembles the human HFpEF phenotype to a large extent characterized by obesity, impaired glucose handling, and metabolic dysregulation accompanied by inflammation