STEP 3 Trial The STEP 3 trial included 611 adults who were overweight or had obesity
(5) R Noordam, D A Gunn, C C Tomlin, A B Maier, et al (2013) Serum insulin-like growth factor 1 and facial ageing: high levels associate with reduced skin wrinkling in a cross-sectional study British Journal of Dermatology, 2013 Mar, Volume 168 (Issue 3), Pages 533-8
For skin wound healing specifically, injection sites should be chosen to deliver peptide near the affected area without injecting directly into damaged tissue
However, the predominance of rodent studies raises questions about translatability to human pathophysiology and therapeutic responses
Avoid repeated freeze-thaw cycling, and verify concentration by UV absorbance at 280 nm where assay design requires it, since the single tryptophan residue gives a usable chromophore