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For one thing, when taken orally they must enter into the general circulation, get broken down by the liver, and then surmount the blood-brain barrier (BBB) a circuitous route
Cobalamin deficiency results in the decrease of this conversion, resulting in high plasma levels of homocysteine, which is associated with a higher risk of cerebrovascular disease, depression, dementia, cellular stress, and apoptosis (25, 27, 64, 70)
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Pharmacy-grade sourcing: your Epithalon is dispensed through a licensed compounding pharmacy