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Aussi, linfluence de la L-carnitine reste suprieure chez les personnes en surpoids ou en tat dobsit (2)
The interaction of active GLP-1R with VAPB was deemed functionally relevant, as it was no longer present when VAPB P56S, a self-aggregating loss-of-function VAPB mutant associated with amyotrophic lateral sclerosis (ALS) 15, 16 , was expressed instead of its wildtype (WT) counterpart (Supplementary Fig
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Previously, combinations of sub-optimal doses of the DACRA KBP-089 and the GLP-1 agonist liraglutide were shown to act complementarily on body weight, food intake and glucose tolerance [13, 14], indicating the add-on potential of KBP-089 to liraglutide in obesity treatment