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Clinical Status Human RCT | Observational | Animal | In vitro Primarily studied in preclinical and exploratory neurophysiological research contexts, with limited controlled human trials
The mechanism of drug-induced vitiligo is uncertain and there are currently autoimmune, neural and cytotoxic theories in relation to this
While preclinical data highlight its therapeutic potential (74), clinical progress has been slow due to unresolved delivery and diagnostic issues (144)
387 The literature on topiroxostat reports certain adverse effects, including polyarthritis, nasopharyngitis, and an increase in liver enzymes
Nicolas, G
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