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Ma L, Peng S, Wei J, Zhao M, Ahmad KA, Chen J et al (2021) Spinal microglial -endorphin signaling mediates IL-10 and exenatide-induced inhibition of synaptic plasticity in neuropathic pain

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Because NAD is a supplement, its not regulated by the FDA and claims around efficacy dont have to be proven (which is required of prescription medications)

Where These Numbers Come From GHRH + GHRP synergy: Bowers et al

A person who wishes to avoid needles may prefer the tablet version